Interstate Soccer Club (ISC) is a youth soccer club serving Sioux City, Iowa, and the greater Siouxland tri-state area. It was created as a unified effort to grow club soccer in the region — bringing together the former South Sioux City Soccer Club and Tristate Revolution Soccer Club and overseeing area recreational leagues — so players of all ages can find the right level of play under one organization.

ISC offers both recreational soccer (through the Sioux City United League) and competitive teams organized into age-specific player pools, supported by a unified board and a team of Directors of Coaching. The club works to keep soccer affordable, offering a scholarship program and payment plans, and is a member of Iowa Soccer.